Activated NF-κB in Bone Marrow Mesenchymal Stem Cells from Systemic Lupus Erythematosus Patients Inhibits Osteogenic Differentiation Through Downregulating Smad Signaling

Osteoporosis in patients with systemic lupus erythematosus (SLE) is thought to be the result of accelerated osteoclastogenesis induced by pro-inflammatory cytokines such as tumor necrosis factor (TNF). However, the molecular mechanisms involved in the osteoblastogenesis in SLE patients are not fully...

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Autori principali: Tang, Yu, Xie, Hao, Chen, Jinyun, Geng, Linyu, Chen, Haifeng, Li, Xia, Hou, Yayi, Lu, Liwei, Shi, Songtao, Zeng, Xiaofeng, Sun, Lingyun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2013
Soggetti:
Original Research Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564481/
https://ncbi.nlm.nih.gov/pubmed/22897816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0226
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