Activated NF-κB in Bone Marrow Mesenchymal Stem Cells from Systemic Lupus Erythematosus Patients Inhibits Osteogenic Differentiation Through Downregulating Smad Signaling

Osteoporosis in patients with systemic lupus erythematosus (SLE) is thought to be the result of accelerated osteoclastogenesis induced by pro-inflammatory cytokines such as tumor necrosis factor (TNF). However, the molecular mechanisms involved in the osteoblastogenesis in SLE patients are not fully...

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Bibliografiska uppgifter
Huvudupphovsmän: Tang, Yu, Xie, Hao, Chen, Jinyun, Geng, Linyu, Chen, Haifeng, Li, Xia, Hou, Yayi, Lu, Liwei, Shi, Songtao, Zeng, Xiaofeng, Sun, Lingyun
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mary Ann Liebert, Inc. 2013
Ämnen:
Original Research Reports
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564481/
https://ncbi.nlm.nih.gov/pubmed/22897816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0226
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