MicroRNA-663 induces immune dysregulation by inhibiting TGF-β1 production in bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus

Mesenchymal stem cells (MSCs) are critical for immune regulation. Although several microRNAs (miRNAs) have been shown to participate in autoimmune pathogenesis by affecting lymphocyte development and function, the roles of miRNAs in MSC dysfunction in autoimmune diseases remain unclear. Here, we sho...

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Veröffentlicht in:Cell Mol Immunol
Hauptverfasser: Geng, Linyu, Tang, Xiaojun, Zhou, Kangxing, Wang, Dandan, Wang, Shiying, Yao, Genhong, Chen, Weiwei, Gao, Xiang, Chen, Wanjun, Shi, Songtao, Shen, Nan, Feng, Xuebing, Sun, Lingyun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6460486/
https://ncbi.nlm.nih.gov/pubmed/30886422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2018.1
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