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Spontaneous calcium waves in Bergman glia increase with age and hypoxia and may reduce tissue oxygen

Glial calcium (Ca(2+)) waves constitute a means to spread signals between glial cells and to neighboring neurons and blood vessels. These waves occur spontaneously in Bergmann glia (BG) of the mouse cerebellar cortex in vivo. Here, we tested three hypotheses: (1) aging and reduced blood oxygen satur...

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Bibliografiske detaljer
Main Authors: Mathiesen, Claus, Brazhe, Alexey, Thomsen, Kirsten, Lauritzen, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564203/
https://ncbi.nlm.nih.gov/pubmed/23211964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.175
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