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Spontaneous calcium waves in Bergman glia increase with age and hypoxia and may reduce tissue oxygen

Glial calcium (Ca(2+)) waves constitute a means to spread signals between glial cells and to neighboring neurons and blood vessels. These waves occur spontaneously in Bergmann glia (BG) of the mouse cerebellar cortex in vivo. Here, we tested three hypotheses: (1) aging and reduced blood oxygen satur...

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Detalhes bibliográficos
Main Authors: Mathiesen, Claus, Brazhe, Alexey, Thomsen, Kirsten, Lauritzen, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564203/
https://ncbi.nlm.nih.gov/pubmed/23211964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.175
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