Activity-dependent Increases in Local Oxygen Consumption Correlate with Postsynaptic Currents in the Mouse Cerebellum In Vivo

Evoked neural activity correlates strongly with rises in cerebral metabolic rate of oxygen (CMRO(2)) and cerebral blood flow (CBF). Activity-dependent rises in CMRO(2) fluctuate with ATP turnover due to ion pumping. In vitro studies suggest that increases in cytosolic Ca(2+) stimulate oxidative meta...

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Pubblicato in:J Neurosci
Autori principali: Mathiesen, Claus, Caesar, Kirsten, Thomsen, Kirsten, Hoogland, Tycho M., Witgen, Brent M., Brazhe, Alexey, Lauritzen, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6623892/
https://ncbi.nlm.nih.gov/pubmed/22171036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4526-11.2011
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