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Activity-dependent Increases in Local Oxygen Consumption Correlate with Postsynaptic Currents in the Mouse Cerebellum In Vivo

Evoked neural activity correlates strongly with rises in cerebral metabolic rate of oxygen (CMRO(2)) and cerebral blood flow (CBF). Activity-dependent rises in CMRO(2) fluctuate with ATP turnover due to ion pumping. In vitro studies suggest that increases in cytosolic Ca(2+) stimulate oxidative meta...

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Publicat a:J Neurosci
Autors principals: Mathiesen, Claus, Caesar, Kirsten, Thomsen, Kirsten, Hoogland, Tycho M., Witgen, Brent M., Brazhe, Alexey, Lauritzen, Martin
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6623892/
https://ncbi.nlm.nih.gov/pubmed/22171036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4526-11.2011
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