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Tumor suppressor protein Pdcd4 interacts with Daxx and modulates the stability of Daxx and the Hipk2-dependent phosphorylation of p53 at serine 46

The tumor suppressor protein Pdcd4 is a nuclear/cytoplasmic shuttling protein that has been implicated in the development of several types of human cancer. In the nucleus, Pdcd4 affects the transcription of specific genes by modulating the activity of several transcription factors. We have identifie...

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Detalhes bibliográficos
Main Authors: Kumar, N, Wethkamp, N, Waters, L C, Carr, M D, Klempnauer, K-H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564021/
https://ncbi.nlm.nih.gov/pubmed/23536002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2012.37
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