Selective glucocorticoid receptor translational isoforms reveal glucocorticoid-induced apoptotic transcriptomes

Induction of T-cell apoptosis contributes to the anti-inflammatory and antineoplastic benefits of glucocorticoids. The glucocorticoid receptor (GR) translational isoforms have distinct proapoptotic activities in osteosarcoma cells. Here we determined whether GR isoforms selectively induce apoptosis...

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Hlavní autoři: Wu, I, Shin, S C, Cao, Y, Bender, I K, Jafari, N, Feng, G, Lin, S, Cidlowski, J A, Schleimer, R P, Lu, N Z
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563981/
https://ncbi.nlm.nih.gov/pubmed/23303127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.193
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