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Genome-wide Gene Deletions in Streptococcus sanguinis by High Throughput PCR

Transposon mutagenesis and single-gene deletion are two methods applied in genome-wide gene knockout in bacteria (1,2). Although transposon mutagenesis is less time consuming, less costly, and does not require completed genome information, there are two weaknesses in this method: (1) the possibility...

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Bibliografische gegevens
Hoofdauteurs: Ge, Xiuchun, Xu, Ping
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MyJove Corporation 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563760/
https://ncbi.nlm.nih.gov/pubmed/23207952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/4356
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