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Trastuzumab-DM1: A Clinical Update of the Novel Antibody-Drug Conjugate for HER2-Overexpressing Breast Cancer

Trastuzumab is a monoclonal antibody targeted against the HER2 tyrosine kinase receptor. Although trastuzumab is a very active agent in HER2-overexpressing breast cancer, the majority of patients with metastatic HER2-overexpressing breast cancer who initially respond to trastuzumab develop resistanc...

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Detalhes bibliográficos
Main Authors: Barginear, Myra F, John, Veena, Budman, Daniel R
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563710/
https://ncbi.nlm.nih.gov/pubmed/23196784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00302
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