Aldo-keto Reductase Family 1 Member C3 (AKR1C3) Is a Biomarker and Therapeutic Target for Castration-Resistant Prostate Cancer

Current endocrine treatment for advanced prostate cancer does not result in a complete ablation of adrenal androgens. Adrenal androgens can be metabolized by prostate cancer cells, which is one of the mechanisms associated with progression to castration-resistant prostate cancer (CRPC). Aldo-keto re...

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Main Authors: Hamid, Agus Rizal A H, Pfeiffer, Minja J, Verhaegh, Gerald W, Schaafsma, Ewout, Brandt, Andre, Sweep, Fred C G J, Sedelaar, John P M, Schalken, Jack A
Format: Artigo
Language:Inglês
Published: ScholarOne 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563708/
https://ncbi.nlm.nih.gov/pubmed/23196782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00296
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