Expression of human FUS protein in Drosophila leads to progressive neurodegeneration

Mutations in the Fused in sarcoma/Translated in liposarcoma gene (FUS/TLS, FUS) have been identified among patients with amyotrophic lateral sclerosis (ALS). FUS protein aggregation is a major pathological hallmark of FUS proteinopathy, a group of neurodegenerative diseases characterized by FUS-immu...

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Autori principali: Chen, Yanbo, Yang, Mengxue, Deng, Jianwen, Chen, Xiaoping, Ye, Ye, Zhu, Li, Liu, Jianghong, Ye, Haihong, Shen, Yan, Li, Yan, Rao, Elizabeth J., Fushimi, Kazuo, Zhou, Xiaohong, Bigio, Eileen H., Mesulam, Marsel, Xu, Qi, Wu, Jane Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Higher Education Press 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563268/
https://ncbi.nlm.nih.gov/pubmed/21748598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1065-7
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