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Transmembrane helix orientation influences membrane binding of the intracellular juxtamembrane domain in Neu receptor peptides
The transmembrane (TM) and juxtamembrane (JM) regions of the ErbB family receptor tyrosine kinases connect the extracellular ligand-binding domain to the intracellular kinase domain. Evidence for the role of these regions in the mechanism of receptor dimerization and activation is provided by TM–JM...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3562775/ https://ncbi.nlm.nih.gov/pubmed/23319611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1215207110 |
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