Wordt geladen...

Explaining why Gleevec is a specific and potent inhibitor of Abl kinase

Tyrosine kinases present attractive drug targets for specific types of cancers. Gleevec, a well-known therapeutic agent against chronic myelogenous leukemia, is an effective inhibitor of Abl tyrosine kinase. However, Gleevec fails to inhibit closely homologous tyrosine kinases, such as c-Src. Becaus...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Lin, Yen-Lin, Meng, Yilin, Jiang, Wei, Roux, Benoît
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562763/
https://ncbi.nlm.nih.gov/pubmed/23319661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214330110
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!