Positive allosteric modulator of alpha 7 nicotinic-acetylcholine receptors, PNU-120596 augments the effects of donepezil on learning and memory in aged rodents and non-human primates

The development of novel therapeutic agents for disorders of cognition such as Alzheimer’s disease (AD) is of paramount importance given the ever-increasing elderly population, however; there is also considerable interest in any strategy that might enhance the clinical efficacy of currently availabl...

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Bibliografiske detaljer
Main Authors: Callahan, Patrick M., Hutchings, Elizabeth J., Kille, Nancy J., Chapman, James M., Terry, Alvin V.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562411/
https://ncbi.nlm.nih.gov/pubmed/23168113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2012.10.019
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