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Neuronal Expression of the Ubiquitin E3 ligase APC/C-Cdh1 During Development is Required for Long-term Potentiation, Behavioral Flexibility, and Extinction

Cdh1 is a regulatory subunit of the Anaphase Promoting Complex/Cyclosome (APC/C), a ubiquitin E3 ligase known to be involved in regulating cell cycle progression. Recent studies have demonstrated a role for Cdh1 in neurons during developmental and adult synaptic plasticity, as well as memory. In ord...

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Detalhes bibliográficos
Main Authors: Pick, Joseph E., Wang, Li, Mayfield, Joshua E., Klann, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562375/
https://ncbi.nlm.nih.gov/pubmed/23238556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nlm.2012.11.005
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