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The “Sharp” blade against HIF-mediated metastasis
Hypoxia-inducible factors (HIFs) control cellular adaptation to oxygen deprivation. Cancer cells engage HIFs to sustain their growth in adverse conditions, thus promoting a cellular reprograming that includes metabolism, proliferation, survival and mobility. HIFs overexpression in human cancer biops...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3562297/ https://ncbi.nlm.nih.gov/pubmed/23187809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22820 |
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