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The “Sharp” blade against HIF-mediated metastasis

Hypoxia-inducible factors (HIFs) control cellular adaptation to oxygen deprivation. Cancer cells engage HIFs to sustain their growth in adverse conditions, thus promoting a cellular reprograming that includes metabolism, proliferation, survival and mobility. HIFs overexpression in human cancer biops...

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Detalhes bibliográficos
Main Authors: Amelio, Ivano, Melino, Gerry
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562297/
https://ncbi.nlm.nih.gov/pubmed/23187809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22820
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