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p73 Alternative Splicing: Exploring a Biological Role for the C-Terminal Isoforms

p73 (encoded by TP73 gene) is a p53 related protein that functions as a transcriptional factor. Similarly to p53, following DNA damage, p73 is stabilized and activated and controls expression of target genes that are involved in the regulation of cycle arrest and apoptosis. However, great complexity...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Vikhreva, Polina, Melino, Gerry, Amelio, Ivano
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995411/
https://ncbi.nlm.nih.gov/pubmed/29733853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2018.04.034
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