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Context is everything: extrinsic signalling and gain-of-function p53 mutants
The TP53 genomic locus is a target of mutational events in at least half of cancers. Despite several decades of study, a full consensus on the relevance of the acquisition of p53 gain-of-function missense mutants has not been reached. Depending on cancer type, type of mutations and other unidentifie...
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| Publicado no: | Cell Death Discov |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7090043/ https://ncbi.nlm.nih.gov/pubmed/32218993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-020-0251-x |
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