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Volatility in mRNA secondary structure as a design principle for antisense

Designing effective antisense sequences is a formidable problem. A method for predicting efficacious antisense holds the potential to provide fundamental insight into this biophysical process. More practically, such an understanding increases the chance of successful antisense design as well as savi...

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Detalles Bibliográficos
Main Authors: Johnson, Erik, Srivastava, Ranjan
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562002/
https://ncbi.nlm.nih.gov/pubmed/23161691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks902
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