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Volatility in mRNA secondary structure as a design principle for antisense

Designing effective antisense sequences is a formidable problem. A method for predicting efficacious antisense holds the potential to provide fundamental insight into this biophysical process. More practically, such an understanding increases the chance of successful antisense design as well as savi...

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Bibliografiske detaljer
Main Authors: Johnson, Erik, Srivastava, Ranjan
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562002/
https://ncbi.nlm.nih.gov/pubmed/23161691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks902
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