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Improved nucleic acid descriptors for siRNA efficacy prediction
Although considerable progress has been made recently in understanding how gene silencing is mediated by the RNAi pathway, the rational design of effective sequences is still a challenging task. In this article, we demonstrate that including three-dimensional descriptors improved the discrimination...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3561943/ https://ncbi.nlm.nih.gov/pubmed/23241392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1191 |
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