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Identification of dosage-sensitive genes in Saccharomyces cerevisiae using the genetic tug-of-war method
Gene overexpression beyond a permissible limit causes defects in cellular functions. However, the permissible limits of most genes are unclear. Previously, we developed a genetic method designated genetic tug-of-war (gTOW) to measure the copy number limit of overexpression of a target gene. In the c...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3561871/ https://ncbi.nlm.nih.gov/pubmed/23275495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.146662.112 |
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