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Microdomains of muscarinic acetylcholine and Ins(1,4,5)P(3) receptors create ‘Ins(1,4,5)P(3) junctions’ and sites of Ca(2+) wave initiation in smooth muscle
Increases in cytosolic Ca(2+) concentration ([Ca(2+)](c)) mediated by inositol (1,4,5)-trisphosphate [Ins(1,4,5)P(3), hereafter InsP(3)] regulate activities that include division, contraction and cell death. InsP(3)-evoked Ca(2+) release often begins at a single site, then regeneratively propagates...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3561854/ https://ncbi.nlm.nih.gov/pubmed/22946060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.105163 |
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