Phosphorylation of the rat Ins(1,4,5)P(3) receptor at T930 within the coupling domain decreases its affinity to Ins(1,4,5)P(3)

The Ins(1,4,5)P(3) receptor acts as a central hub for Ca(2+) signaling by integrating multiple signaling modalities into Ca(2+) release from intracellular stores downstream of G-protein and tyrosine kinase-coupled receptor stimulation. As such, the Ins(1,4,5)P(3) receptor plays fundamental roles in...

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Hlavní autoři: Haun, Shirley, Sun, Lu, Hubrack, Satanay, Yule, David, Machaca, Khaled
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2012
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508777/
https://ncbi.nlm.nih.gov/pubmed/22878752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.21170
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