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Phosphorylation of the rat Ins(1,4,5)P(3) receptor at T930 within the coupling domain decreases its affinity to Ins(1,4,5)P(3)
The Ins(1,4,5)P(3) receptor acts as a central hub for Ca(2+) signaling by integrating multiple signaling modalities into Ca(2+) release from intracellular stores downstream of G-protein and tyrosine kinase-coupled receptor stimulation. As such, the Ins(1,4,5)P(3) receptor plays fundamental roles in...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Landes Bioscience
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3508777/ https://ncbi.nlm.nih.gov/pubmed/22878752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.21170 |
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