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Phosphorylation of the rat Ins(1,4,5)P(3) receptor at T930 within the coupling domain decreases its affinity to Ins(1,4,5)P(3)
The Ins(1,4,5)P(3) receptor acts as a central hub for Ca(2+) signaling by integrating multiple signaling modalities into Ca(2+) release from intracellular stores downstream of G-protein and tyrosine kinase-coupled receptor stimulation. As such, the Ins(1,4,5)P(3) receptor plays fundamental roles in...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Landes Bioscience
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3508777/ https://ncbi.nlm.nih.gov/pubmed/22878752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.21170 |
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