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Regulation of cerebellar Ins(1,4,5)P3 receptor by interaction between Ins(1,4,5)P3 and Ca2+.

We have characterized in detail the Ca(2+)-dependent inhibition of [(3)H]Ins(1,4,5)P(3) ([(3)H]InsP(3)) binding to sheep cerebellar microsomes, over a short duration (3 s), with the use of a perfusion protocol. This procedure prevented artifacts previously identified in studies of this Ca(2+) effect...

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Main Authors: Coquil, J F, Picard, L, Mauger, J P
格式: Artigo
語言:Inglês
出版: 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220408/
https://ncbi.nlm.nih.gov/pubmed/10417334
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