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Upon Wnt stimulation, Rac1 activation requires Rac1 and Vav2 binding to p120-catenin
A role for Rac1 GTPase in canonical Wnt signaling has recently been demonstrated, showing that it is required for β-catenin translocation to the nucleus. In this study, we investigated the mechanism of Rac1 stimulation by Wnt. Upregulation of Rac1 activity by Wnt3a temporally correlated with enhance...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Company of Biologists
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3561852/ https://ncbi.nlm.nih.gov/pubmed/22946057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.101030 |
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