EWS/ATF1 expression induces sarcomas from neural crest–derived cells in mice

Clear cell sarcoma (CCS) is an aggressive soft tissue malignant tumor characterized by a unique t(12;22) translocation that leads to the expression of a chimeric EWS/ATF1 fusion gene. However, little is known about the mechanisms underlying the involvement of EWS/ATF1 in CCS development. In addition...

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Detalhes bibliográficos
Main Authors: Yamada, Kazunari, Ohno, Takatoshi, Aoki, Hitomi, Semi, Katsunori, Watanabe, Akira, Moritake, Hiroshi, Shiozawa, Shunichi, Kunisada, Takahiro, Kobayashi, Yukiko, Toguchida, Junya, Shimizu, Katsuji, Hara, Akira, Yamada, Yasuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561811/
https://ncbi.nlm.nih.gov/pubmed/23281395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63572
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