Platelet ITAM signaling is critical for vascular integrity in inflammation

Platelets play a critical role in maintaining vascular integrity during inflammation, but little is known about the underlying molecular mechanisms. Here we report that platelet immunoreceptor tyrosine activation motif (ITAM) signaling, but not GPCR signaling, is critical for the prevention of infla...

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Bibliographische Detailangaben
Hauptverfasser: Boulaftali, Yacine, Hess, Paul R., Getz, Todd M., Cholka, Agnieszka, Stolla, Moritz, Mackman, Nigel, Owens, A. Phillip, Ware, Jerry, Kahn, Mark L., Bergmeier, Wolfgang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561801/
https://ncbi.nlm.nih.gov/pubmed/23348738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65154
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