Platelet ITAM signaling is critical for vascular integrity in inflammation

Platelets play a critical role in maintaining vascular integrity during inflammation, but little is known about the underlying molecular mechanisms. Here we report that platelet immunoreceptor tyrosine activation motif (ITAM) signaling, but not GPCR signaling, is critical for the prevention of infla...

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Hlavní autoři: Boulaftali, Yacine, Hess, Paul R., Getz, Todd M., Cholka, Agnieszka, Stolla, Moritz, Mackman, Nigel, Owens, A. Phillip, Ware, Jerry, Kahn, Mark L., Bergmeier, Wolfgang
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561801/
https://ncbi.nlm.nih.gov/pubmed/23348738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65154
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