Platelet ITAM signaling is critical for vascular integrity in inflammation

Platelets play a critical role in maintaining vascular integrity during inflammation, but little is known about the underlying molecular mechanisms. Here we report that platelet immunoreceptor tyrosine activation motif (ITAM) signaling, but not GPCR signaling, is critical for the prevention of infla...

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Main Authors: Boulaftali, Yacine, Hess, Paul R., Getz, Todd M., Cholka, Agnieszka, Stolla, Moritz, Mackman, Nigel, Owens, A. Phillip, Ware, Jerry, Kahn, Mark L., Bergmeier, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561801/
https://ncbi.nlm.nih.gov/pubmed/23348738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65154
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