Platelet ITAM signaling is critical for vascular integrity in inflammation

Platelets play a critical role in maintaining vascular integrity during inflammation, but little is known about the underlying molecular mechanisms. Here we report that platelet immunoreceptor tyrosine activation motif (ITAM) signaling, but not GPCR signaling, is critical for the prevention of infla...

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Detalhes bibliográficos
Main Authors: Boulaftali, Yacine, Hess, Paul R., Getz, Todd M., Cholka, Agnieszka, Stolla, Moritz, Mackman, Nigel, Owens, A. Phillip, Ware, Jerry, Kahn, Mark L., Bergmeier, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561801/
https://ncbi.nlm.nih.gov/pubmed/23348738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65154
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