Platelet Inhibitors Reduce Rupture in a Mouse Model of Established Abdominal Aortic Aneurysm

OBJECTIVE: Rupture of abdominal aortic aneurysms (AAAs) causes a high morbidity and mortality in the elderly population. Platelet-rich thrombi form on the surface of aneurysms and may contribute to disease progression. In this study, we used a pharmacologic approach to examine a role of platelets in...

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Vydáno v:Arterioscler Thromb Vasc Biol
Hlavní autoři: Owens, A. Phillip, Edwards, Todd L, Antoniak, Silvio, Geddings, Julia E., Jahangir, Eiman, Wei, Wei-Qi, Denny, Joshua C., Boulaftali, Yacine, Bergmeier, Wolfgang, Daugherty, Alan, Sampson, Uchechukwu K.A., Mackman, Nigel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552620/
https://ncbi.nlm.nih.gov/pubmed/26139462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.305537
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