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Specialized role of migratory dendritic cells in peripheral tolerance induction

Harnessing DCs for immunotherapies in vivo requires the elucidation of the physiological role of distinct DC populations. Migratory DCs traffic from peripheral tissues to draining lymph nodes charged with tissue self antigens. We hypothesized that these DC populations have a specialized role in the...

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Detalhes bibliográficos
Main Authors: Idoyaga, Juliana, Fiorese, Christopher, Zbytnuik, Lori, Lubkin, Ashira, Miller, Jennifer, Malissen, Bernard, Mucida, Daniel, Merad, Miriam, Steinman, Ralph M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561796/
https://ncbi.nlm.nih.gov/pubmed/23298832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65260
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