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Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
The immune system generally avoids horror autotoxicus or autoimmunity, an attack against the body's own constituents. This avoidance requires that self-reactive T cells be actively silenced or tolerized. We propose that dendritic cells (DCs) play a critical role in establishing tolerance, espec...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The National Academy of Sciences
2002
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC117564/ https://ncbi.nlm.nih.gov/pubmed/11773639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231606698 |
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