Sox17 haploinsufficiency results in perinatal biliary atresia and hepatitis in C57BL/6 background mice

Congenital biliary atresia is an incurable disease of newborn infants, of unknown genetic causes, that results in congenital deformation of the gallbladder and biliary duct system. Here, we show that during mouse organogenesis, insufficient SOX17 expression in the gallbladder and bile duct epithelia...

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Main Authors: Uemura, Mami, Ozawa, Aisa, Nagata, Takumi, Kurasawa, Kaoruko, Tsunekawa, Naoki, Nobuhisa, Ikuo, Taga, Tetsuya, Hara, Kenshiro, Kudo, Akihiko, Kawakami, Hayato, Saijoh, Yukio, Kurohmaru, Masamichi, Kanai-Azuma, Masami, Kanai, Yoshiakira
Format: Artigo
Jezik:Inglês
Izdano: Company of Biologists 2013
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561787/
https://ncbi.nlm.nih.gov/pubmed/23293295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.086702
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