The Transcription Factor Paired-Related Homeobox 1 (Prrx1) Inhibits Adipogenesis by Activating Transforming Growth Factor-β (TGFβ) Signaling

Differentiation of adipocytes from preadipocytes contributes to adipose tissue expansion in obesity. Impaired adipogenesis may underlie the development of metabolic diseases such as insulin resistance and type 2 diabetes. Mechanistically, a well defined transcriptional network coordinates adipocyte...

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Detalhes bibliográficos
Main Authors: Du, Baowen, Cawthorn, William P., Su, Alison, Doucette, Casey R., Yao, Yao, Hemati, Nahid, Kampert, Sarah, McCoin, Colin, Broome, David T., Rosen, Clifford J., Yang, Gongshe, MacDougald, Ormond A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561528/
https://ncbi.nlm.nih.gov/pubmed/23250756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.440370
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