Cyclophilin D Deficiency Rescues Axonal Mitochondrial Transport in Alzheimer’s Neurons

Normal axonal mitochondrial transport and function is essential for the maintenance of synaptic function. Abnormal mitochondrial motility and mitochondrial dysfunction within axons are critical for amyloid β (Aβ)-induced synaptic stress and the loss of synapses relevant to the pathogenesis of Alzhei...

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Bibliografiske detaljer
Main Authors: Guo, Lan, Du, Heng, Yan, Shiqiang, Wu, Xiaoping, McKhann, Guy M., Chen, John Xi, Yan, Shirley ShiDu
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561411/
https://ncbi.nlm.nih.gov/pubmed/23382999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054914
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