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Versatile inhibitory effects of the flavonoid-derived PI3K/Akt inhibitor, LY294002, on ATP-binding cassette transporters that characterize stem cells

Stem cells are undifferentiated cells capable of proliferation, self-renewal, and production of a large number of differentiated progeny. Stem cells exist even in malignancies. They are called cancer stem cells, which may represent the origin of these tumors and may be one of the reasons of chemores...

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Bibliografiske detaljer
Main Authors: Imai, Yasuo, Yamagishi, Hidetsugu, Ono, Yuko, Ueda, Yoshihiko
Format: Artigo
Sprog:Inglês
Udgivet: Springer 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560972/
https://ncbi.nlm.nih.gov/pubmed/23369170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2001-1326-1-24
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