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Versatile inhibitory effects of the flavonoid-derived PI3K/Akt inhibitor, LY294002, on ATP-binding cassette transporters that characterize stem cells

Stem cells are undifferentiated cells capable of proliferation, self-renewal, and production of a large number of differentiated progeny. Stem cells exist even in malignancies. They are called cancer stem cells, which may represent the origin of these tumors and may be one of the reasons of chemores...

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Detalhes bibliográficos
Main Authors: Imai, Yasuo, Yamagishi, Hidetsugu, Ono, Yuko, Ueda, Yoshihiko
Formato: Artigo
Idioma:Inglês
Publicado em: Springer 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560972/
https://ncbi.nlm.nih.gov/pubmed/23369170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2001-1326-1-24
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