טוען...

Effect of Rifampicin on S-ketamine and S-norketamine Plasma Concentrations in Healthy Volunteers after Intravenous S-ketamine Administration

BACKGROUND: Low-dose ketamine is used as analgesic for acute and chronic pain. It is metabolized in the liver to norketamine via cytochrome P450 enzymes. There are few human data on the involvement of CYP enzymes on the elimination of norketamine and its possible contribution to analgesic effect. Th...

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מידע ביבליוגרפי
Main Authors: Noppers, Ingeborg, Olofsen, Erik, Niesters, Marieke, Aarts, Leon, Mooren, René, Dahan, Albert, Kharasch, Evan, Sarton, Elise
פורמט: Artigo
שפה:Inglês
יצא לאור: 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560924/
https://ncbi.nlm.nih.gov/pubmed/21508826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e318218a881
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