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Small-molecule inhibitors of DNA damage-repair pathways: an approach to overcome tumor resistance to alkylating anticancer drugs

A major challenge in the future development of cancer therapeutics is the identification of biological targets and pathways, and the subsequent design of molecules to combat the drug-resistant cells hiding in virtually all cancers. This therapeutic approach is justified based upon the limited advanc...

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Detalhes bibliográficos
Main Authors: Srinivasan, Ajay, Gold, Barry
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560920/
https://ncbi.nlm.nih.gov/pubmed/22709253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.12.58
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