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Small-molecule drug repurposing to target DNA damage repair and response pathways
For decades genotoxic therapy has been a mainstay in the treatment of cancer, based on the understanding that the deregulated growth and genomic instability that drive malignancy also confer a shared vulnerability. Although chemotherapy and radiation can be curative, only a fraction of patients bene...
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| Wydane w: | Semin Cancer Biol |
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| Główni autorzy: | , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2020
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7483256/ https://ncbi.nlm.nih.gov/pubmed/32113999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2020.02.013 |
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