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Cav1 inhibits benign skin tumor development in a two-stage carcinogenesis model by suppressing epidermal proliferation

Caveolin-1 (Cav1) is the main protein component of the membrane lipid rafts caveolae. Cav1 serves as a scaffolding protein that compartmentalizes a multitude of signaling molecules and sequesters them in their inactive state. Due to its function in the negative regulation of signal transduction, los...

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Bibliografiska uppgifter
Huvudupphovsmän: Trimmer, Casey, Sotgia, Federica, Lisanti, Michael P, Capozza, Franco
Materialtyp: Artigo
Språk:Inglês
Publicerad: e-Century Publishing Corporation 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560478/
https://ncbi.nlm.nih.gov/pubmed/23390568
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