STAT1 Is Essential for Antimicrobial Effector Function but Dispensable for Gamma Interferon Production during Toxoplasma gondii Infection

The opportunistic protozoan Toxoplasma gondii is a prototypic Th1-inducing pathogen inducing strong gamma interferon (IFN-γ) cytokine responses that are required to survive infection. Intracellular signaling intermediate STAT1 mediates many effects of IFN-γ and is implicated in activation of T-bet,...

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Dettagli Bibliografici
Pubblicato in:Infect Immun
Autori principali: Gavrilescu, L. Cristina, Butcher, Barbara A., Del Rio, Laura, Taylor, Gregory A., Denkers, Eric Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2004
Soggetti:
Fungal and Parasitic Infections
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC356043/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14977926/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.3.1257-1264.2004
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