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Novel Antigen Identification Method for Discovery of Protective Malaria Antigens by Rapid Testing of DNA Vaccines Encoding Exons from the Parasite Genome

We describe a novel approach for identifying target antigens for preerythrocytic malaria vaccines. Our strategy is to rapidly test hundreds of DNA vaccines encoding exons from the Plasmodium yoelii yoelii genomic sequence. In this antigen identification method, we measure reduction in parasite burde...

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Detalhes bibliográficos
Main Authors: Haddad, Diana, Bilcikova, Erika, Witney, Adam A., Carlton, Jane M., White, Charles E., Blair, Peter L., Chattopadhyay, Rana, Russell, Joshua, Abot, Esteban, Charoenvit, Yupin, Aguiar, Joao C., Carucci, Daniel J., Weiss, Walter R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC356014/
https://ncbi.nlm.nih.gov/pubmed/14977966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.3.1594-1602.2004
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