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mVps34 Deletion in Podocytes Causes Glomerulosclerosis by Disrupting Intracellular Vesicle Trafficking

Recent studies have suggested that autophagy is a key mechanism in maintaining the integrity of podocytes. The mammalian homologue of yeast vacuolar protein sorting defective 34 (mVps34) has been implicated in the regulation of autophagy, but its role in podocytes is unknown. We generated a line of...

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Detalhes bibliográficos
Main Authors: Chen, Jianchun, Chen, Mystie X., Fogo, Agnes B., Harris, Raymond C., Chen, Jian-Kang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3559479/
https://ncbi.nlm.nih.gov/pubmed/23291473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012010101
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