Synaptic vesicles position complexin to block spontaneous fusion

Synapses continually replenish their synaptic vesicle (SV) pools while suppressing spontaneous fusion events, thus maintaining a high dynamic range in response to physiological stimuli. The presynaptic protein complexin can both promote and inhibit fusion through interactions between its alpha-helic...

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Bibliographic Details
Main Authors: Wragg, Rachel T., Snead, David, Dong, Yongming, Ramlall, Trudy F., Menon, Indu, Bai, Jihong, Eliezer, David, Dittman, Jeremy S
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3559010/
https://ncbi.nlm.nih.gov/pubmed/23352168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.11.005
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