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ELANE Mutations in Cyclic and Severe Congenital Neutropenia—Genetics and Pathophysiology
There are two main forms of hereditary neutropenia: cyclic and severe congenital neutropenia (SCN). Cyclic neutropenia is an autosomal dominant disorder in which neutrophil counts fluctuate between nearly normal levels and close to zero with 21-day periodicity. In contrast, SCN, also known as Kostma...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3559001/ https://ncbi.nlm.nih.gov/pubmed/23351986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hoc.2012.10.004 |
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