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Modulation of reactivity and conformation within the T quaternary state of human hemoglobin: the combined use of mutagenesis and sol-gel encapsulation

A range of conformationally-distinct functional states within the T quaternary state of hemoglobin are accessed and probed using a combination of mutagenesis and sol-gel encapsulation that greatly slow or eliminate the T→R transition. Visible and UV resonance Raman spectroscopy are used to probe the...

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Bibliografische gegevens
Hoofdauteurs: Samuni, Uri, Roche, Camille J., Dantsker, David, Juszczak, Laura J., Friedman, Joel M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558951/
https://ncbi.nlm.nih.gov/pubmed/16503637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi050010i
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