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Generating S-Nitrosothiols from Hemoglobin: MECHANISMS, CONFORMATIONAL DEPENDENCE, AND PHYSIOLOGICAL RELEVANCE
In vitro, ferrous deoxy-hemes in hemoglobin (Hb) react with nitrite to generate nitric oxide (NO) through a nitrite reductase reaction. In vivo studies indicate Hb with nitrite can be a source of NO bioactivity. The nitrite reductase reaction does not appear to account fully for this activity becaus...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3829331/ https://ncbi.nlm.nih.gov/pubmed/23775069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.482679 |
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